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'''Leydig Cell Hypoplasia''' or '''LCH''' is an extremely rare [[intersex]] variation<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/#frequency</ref> that effects [[AMAB]]/[[CTM]] individuals in which the Leydig Cell (a cell that secretes androgens) is underdeveloped.
The cells underdevelopment causes a decrease in androgens and may cause ones male traits to be more [[feminine]] in nature. One with this variation tends to have [[Ambiguous Genitalia|ambiguous genitals]]/fall on the [[agenital]] spectrum, [[hypospadias]], decreased body hair, and [[Secondary Sex Agenesis|decreased muscle tone]]. In rare cases, they may have a vagina. Often [[AMAB Hypogonadism|AMAB hypogonadism]] is seen in these individuals as well, which may cause them to also fall under [[Aromatase Excess Syndrome|aromatase excess syndrome]].<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/</ref>
== History ==
There is no findable confirmation of its original discovery, however it has been known since 1995.<ref>https://www.cell.com/ajhg/pdf/S0002-9297(07)62597-X.pdf</ref>
== References ==
<references />
[[Category:Intersex Traits]]
[[Category:Flagless Sexes]]
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