AMAB Hypogonadism is a form of hypogonadism leading to a reduction in the output of male sex hormones in AMAB people due to decreased functionality of the testes. Hypogonadism can be primary, meaning it's caused by a problem with the testicles, or it can be secondary hypogonadism, meaning it's caused by a problem with the signals sent from the brain to the testicles.
Hypogonadism can be congenital or it can be acquired. Congenital hypogonadism can be caused by Klinefelter’s syndrome, gene mutations, chromosomal abnormalities, or other conditions of intersex. This form of is typically not noticed until the onset of puberty. Acquired hypogonadism may be caused by infections, radiation, certain autoimmune disorders, some chronic illnesses, or damage to the pituitary gland.
Symptoms will include the effects of low testosterone, including low energy, fatigue, and a lower sex drive. Those with congenital hypogonadism are usually diagnosed because they will not have started puberty.