[[File:Prader willi syndrome.jpg|thumb|The Prader-Willi Syndrome flag.]]
'''Prader–Willi syndrome''' ('''PWS''') is a conditionsyndrome that - in some cases - may be considered an [[intersex]] conditionvariation, although many would say it ''causes'' intersex conditionstraits rather than being one in of itself. Prader-Willi syndrome affects an estimated 1 in 10,000 to 30,000 people worldwide.
This conditionsyndrome can cause [[hypogonadism]] and [[Agenital|underdeveloped genitals]] (in both [[CTF]] and [[CTM]] individuals) within the people it effects, putting them on the intersex spectrum.
Those with this conditionsyndrome often have [[Secondary Sex Agenesis|weak muscle tone (hypotonia)]], feeding difficulties, poor growth, delayed development, speech delay, crossed eyes, poor physical coordination, infertility, sparse pubic hair, short stature, a narrow forehead, almond-shaped eyes, a down-turned mouth, small hands and feet, fair skin, light hair, and delayed or incomplete puberty. They also typically have an insatiable appetite which causes overeating and obesity. Typically, one with this conditionsyndrome develops type two diabetes.
Sleep abnormalites, behavioral problems, outbursts, and compulsive habits are also common with those who have this conditionsyndrome.
It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this conditionsyndrome, as someone may only experience one or several of these symptoms, yet still hold the conditionsyndrome.
== Causes ==
Normally, a fetus inherits an imprinted maternal copy of PW genes and a functional paternal copy of PW genes. Due to imprinting, the maternally inherited copies of these genes are virtually silent, and the fetus therefore relies on the expression of the paternal copies of the genes. In PWS, however, there is mutation/deletion of the paternal copies of PW genes, leaving the fetus with no functioning PW genes, and causing this conditionsyndrome and its symptoms.
== Flag ==
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