Content added Content deleted
(Adding categories) |
Cryptocrew (talk | contribs) (Added information.) |
||
| Line 1: | Line 1: | ||
'''Leydig Cell Hypoplasia''' or '''LCH''' is an extremely rare [[intersex]] variation<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/#frequency</ref> that effects [[AMAB]]/[[CTM]] individuals in which the Leydig Cell (a cell that secretes androgens) is underdeveloped.<ref>https://en.wikipedia.org/wiki/Leydig_cell_hypoplasia</ref> |
'''Leydig Cell Hypoplasia''' or '''LCH''' is an extremely rare [[intersex]] variation<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/#frequency</ref> that effects [[AMAB]]/[[CTM]] individuals in which the Leydig Cell (a cell that secretes androgens) is underdeveloped.<ref>https://en.wikipedia.org/wiki/Leydig_cell_hypoplasia</ref> |
||
The cells underdevelopment causes a decrease in androgens and may cause ones male traits to be more [[feminine]] in nature. |
|||
| ⚫ | |||
One with this variation tends to have [[Ambiguous Genitalia|ambiguous genitals]], [[agenital|micropenis]], a penis with [[hypospadias]] and/or a bifid scrotum, decreased body hair, and [[Secondary Sex Agenesis|decreased muscle tone]]. In more extreme cases, they may have a vagina, with their testicles being small (microorchidism) and undescended (cryptorchidism). |
|||
| ⚫ | Often [[AMAB Hypogonadism|AMAB hypogonadism]] is seen in these individuals as well, which may cause them to also fall under [[Aromatase Excess Syndrome|aromatase excess syndrome]].<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/</ref><ref>https://www.cell.com/ajhg/pdf/S0002-9297(07)62597-X.pdf</ref> |
||
== References == |
== References == |
||
<references /> |
<references /> |
||
Latest revision as of 01:57, 25 January 2023
Leydig Cell Hypoplasia or LCH is an extremely rare intersex variation[1] that effects AMAB/CTM individuals in which the Leydig Cell (a cell that secretes androgens) is underdeveloped.[2]
The cells underdevelopment causes a decrease in androgens and may cause ones male traits to be more feminine in nature.
One with this variation tends to have ambiguous genitals, micropenis, a penis with hypospadias and/or a bifid scrotum, decreased body hair, and decreased muscle tone. In more extreme cases, they may have a vagina, with their testicles being small (microorchidism) and undescended (cryptorchidism).
Often AMAB hypogonadism is seen in these individuals as well, which may cause them to also fall under aromatase excess syndrome.[3][4]