Leydig Cell Hypoplasia: Difference between revisions

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-'''Leydig Cell Hypoplasia''' or '''LCH''' is an extremely rare [[intersex]] variation that effects [[AMAB]]/[[CTM]] individuals in which the Leydig Cell (a cell that secretes androgens) is underdeveloped. This underdevelopment causes a decrease in androgens and may cause ones male traits to be more [[feminine]] in nature. One with this variation tends to have [[Ambiguous Genitalia|ambiguous genitals]] or otherwise fall on the [[agenital]] spectrum, [[hypospadias]], decreased body hair, and [[Secondary Sex Agenesis|decreased muscle tone]].
+'''Leydig Cell Hypoplasia''' or '''LCH''' is an extremely rare [[intersex]] variation<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/#frequency</ref> that effects [[AMAB]]/[[CTM]] individuals in which the Leydig Cell (a cell that secretes androgens) is underdeveloped.<ref>https://en.wikipedia.org/wiki/Leydig_cell_hypoplasia</ref>
-Often [[AMAB Hypogonadism|AMAB hypogonadism]] is seen in these individuals as well, which may cause them to also fall under [[Aromatase Excess Syndrome|aromatase excess syndrome]].
+The cells underdevelopment causes a decrease in androgens and may cause ones male traits to be more [[feminine]] in nature. One with this variation tends to have [[Ambiguous Genitalia|ambiguous genitals]]/fall on the [[agenital]] spectrum, [[hypospadias]], decreased body hair, and [[Secondary Sex Agenesis|decreased muscle tone]]. In rare cases, they may have a vagina. Often [[AMAB Hypogonadism|AMAB hypogonadism]] is seen in these individuals as well, which may cause them to also fall under [[Aromatase Excess Syndrome|aromatase excess syndrome]].<ref>https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/</ref>
-It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this variation, as someone may only experience one or several of these symptoms, yet still hold the variation.
 == History ==
-There is no confirmation of its original discovery, however it has been known since 1995.
+There is no findable confirmation of its original discovery, however it has been known since 1995.<ref>https://www.cell.com/ajhg/pdf/S0002-9297(07)62597-X.pdf</ref>
-== Resources ==
+== References ==
-* https://medlineplus.gov/genetics/condition/leydig-cell-hypoplasia/#frequency
+<references />
-* https://en.wikipedia.org/wiki/Leydig_cell_hypoplasia
-* https://www.cell.com/ajhg/pdf/S0002-9297(07)62597-X.pdf
 [[Category:Intersex Traits]]
 [[Category:Flagless Sexes]]