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AMAB individuals with this condition may have a penis, however they often have [[Ambiguous Genitalia|ambiguous genitals]], [[Agenital|undescended testicles (cryptorchidism)]], or a vagina. Because of this, they typically are infertile and unable to bare children. They also typically have [[gonadal dysgenesis]] as well. |
AMAB individuals with this condition may have a penis, however they often have [[Ambiguous Genitalia|ambiguous genitals]], [[Agenital|undescended testicles (cryptorchidism)]], or a vagina. Because of this, they typically are infertile and unable to bare children. They also typically have [[gonadal dysgenesis]] as well. |
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AFAB individuals with this condition have a vagina, |
AFAB individuals with this condition have a vagina, while the only noticeable trait of DDS is their kidneys. Because of this, they are often diagnosed with other kidney-related conditions, rather than with DDS. |
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== Resources == |
== Resources == |
Revision as of 12:21, 24 April 2021
Denys-Drash Syndrome (DDS) is an intersex trait that effects both AFAB and AMAB individuals. It has only around 150-200 reports, however it may be more frequent than this, just without notice. This condition is caused when one WT1 gene- a gene designed for connecting regions of DNA together- fails to properly function. Because of this, proteins that effect genitals and kidneys are effected during development in the womb.
Those with this condition have diffuse glomerulosclerosis, which is a condition that effects ones kidneys abilities to filter waste. Because of this, they have a 90% chance at gaining Wilms tumor, a rare kidney cancer.
AMAB individuals with this condition may have a penis, however they often have ambiguous genitals, undescended testicles (cryptorchidism), or a vagina. Because of this, they typically are infertile and unable to bare children. They also typically have gonadal dysgenesis as well.
AFAB individuals with this condition have a vagina, while the only noticeable trait of DDS is their kidneys. Because of this, they are often diagnosed with other kidney-related conditions, rather than with DDS.