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    Cytochrome PORD: Difference between revisions

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    [[File:Cpord.jpg|thumb|The CPORD flag.|200x200px]]
    [[File:Cpord.jpg|thumb|The CPORD flag.|200x200px]]
    '''Cytochrome PORD (CPORD)''' is an [[intersex]] variation that effects both [[CTM]] and [[CTF]] individuals alike. This variation is characterized by a mutation in horomones, which causes one to gain [[hypogonadism]], and have a lack of testosterone and estrogen alike. It is unknown how common this variation is, as only 65 cases have been reported.
    '''Cytochrome PORD (CPORD)''' is an [[intersex]] variation that effects both [[CTM]] and [[CTF]] individuals alike. This variation is characterized by a mutation in horomones, which causes one to gain [[hypogonadism]], and have a lack of testosterone and estrogen alike. It is unknown how common this variation is, as only 65 cases have been reported.<ref>https://medlineplus.gov/genetics/condition/cytochrome-p450-oxidoreductase-deficiency/</ref>


    For those with this variation, [[Ambiguous Genitalia|ambiguous genitals]] and infertility is common amongst both CTM and CTF individuals.
    For those with this variation, [[Ambiguous Genitalia|ambiguous genitals]] and infertility is common amongst both CTM and CTF individuals.


    For CTF individuals, amenorrhea, ovarian cysts, and [[hyperandrogenism]] is common. Because of this, CTF individuals tend to have masculinized traits that cause irregular menstruation, acne, excessive body hair, and weight gain.
    For CTF individuals, amenorrhea, ovarian cysts, and [[hyperandrogenism]] is common. Because of this, CTF individuals tend to have masculinized traits that cause irregular menstruation, acne, excessive body hair, and weight gain.

    It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this variation, as someone may only experience one or several of these symptoms, yet still hold the variation.


    == Antley-Bixler Syndrome ==
    == Antley-Bixler Syndrome ==
    Line 16: Line 14:


    == Causes ==
    == Causes ==
    This variation is caused by mutations in the POR gene, a gene that provides instructions for enzymes that play a critical role in steroid horomones. Because of this mutation, horomones such as testosterone and estrogen become very low in production, and don't balance correctly within the body.
    This variation is caused by mutations in the POR gene, a gene that provides instructions for enzymes that play a critical role in steroid hormones. Because of this mutation, hormones such as testosterone and estrogen become very low in production, and don't balance correctly within the body.


    == Pregnancy ==
    == Pregnancy ==
    Individuals who are pregnant with children who have CPORD and/or ABS tend to develop some symptoms themselves while the baby is forming. This includes development of excessive body hair, acne, and a deepening voice. These changes slowly go away after the baby is delivered.
    Individuals who are pregnant with children who have CPORD and/or ABS tend to develop some symptoms themselves while the baby is forming. This includes development of excessive body hair, acne, and a deepening voice. These changes slowly go away after the baby is delivered.


    The reasoning for this is due to horomonal disturbance effecting not only the baby, but the carrier of the baby as well during development.
    The reasoning for this is due to hormonal disturbance effecting not only the baby, but the carrier of the baby as well during development.


    == Flag ==
    == Flag ==
    The CPORD flag was coined by [[User:Reign of the breadsticcs|Reign of the breadsticcs]] on May 7th of 2021. It has no confirmed meaning.
    The CPORD flag was coined by [[User:Reign of the breadsticcs|Reign of the breadsticcs]] on May 7th of 2021. It has no confirmed meaning.<ref>https://lgbta.wikia.org/f/p/4400000000000137332/r/4400000000000449105</ref>


    == Resources ==
    == Resources ==


    * https://medlineplus.gov/genetics/condition/cytochrome-p450-oxidoreductase-deficiency/#causes
    * https://medlineplus.gov/genetics/condition/cytochrome-p450-oxidoreductase-deficiency/#causes
    *
    *https://lgbta.wikia.org/f/p/4400000000000137332/r/4400000000000449105


    [[Category:Intersex Traits]]
    [[Category:Intersex Traits]]
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