Chromosome 18 Ring

File:Screenshot 2021-04-30 at 6.04.32 PM.png

The Chromosome 18 Ring flag.

Chromosome 18 Ring is a condition that - in some cases - may be considered an intersex condition, although many would say it causes intersex conditions rather than being one in of itself. This condition is seemingly rare, with no known estimates.

This condition can cause a missing or undescended testicle, a micropenis, and/or hypospadias in CTM/AMAB individuals. Amongst CTF/AFAB individuals with this condition tend to have labial hypoplasia (one or both labias missing.)

This condition often comes with low muscle tone, strabismus, hearing loss, undersized kidneys, foot abnormalties, scoliosis, rib-cage abnormalities, umbilical and inguinal hernias, and brain defects that often lead one to fall on the autism spectrum.

Causes

This condition is caused when there is a defect, loss, or deletion in the 18th chromosome, which causes the ending of other chromosomes to form a ring. This chromosomal abnormality causes the formation during the fetal stage to change, and causes development to be different than usual. This could affect all cells, however it usually only affects a small handful of them.

History

This condition was first reported in 1964.

Flag

The flag was designed by FANDOM user Poggingcameron on April 30th of 2021. The blue signifies the lack of a missing or undescended testicle, the ring represents the chromosomes ending in a ring, and the minus signifies the lack of estimated people with the condition

Resources

• https://rarediseases.org/rare-diseases/chromosome-18-ring/
• https://en.wikipedia.org/wiki/Ring_chromosome_18