[[File:Screenshot 2021-04-30 at 6.04.32 PM.png|thumb|234x234px|The Chromosome 18 Ring flag. ]]'''Chromosome 18 Ring''' is a conditionsyndrome that - in some cases - may be considered an [[intersex]] conditionvariation, although many would say it ''causes'' intersex conditionstraits rather than being one in of itself. This conditionsyndrome is seemingly rare, with no known estimates.
This conditionsyndrome can cause a [[Agenital|missing or undescended testicle, a micropenis]], and/or [[hypospadias]] in [[CTM]]/[[AMAB]] individuals. Amongst CTF/AFAB individuals with this conditionsyndrome tend to have labial hypoplasia (one or both labiaslabia missing.)
This conditionsyndrome often comes with [[Secondary Sex Agenesis|low muscle tone]], strabismus, hearing loss, undersized kidneys, foot abnormaltiesabnormalities, scoliosis, rib-cage abnormalities, umbilical and inguinal hernias, and brain defects that often lead one to fall on the [[Neurodivergent|autism spectrum.]] Some of these symptoms may classify one with this syndrome as physically [[disabled]].<ref>{{Archive|Site=web|URL=https://rarediseases.org/rare-diseases/chromosome-18-ring/}}</ref>
== Causes ==
This conditionsyndrome is caused when there is a defect, loss, or deletion in the 18th chromosome, which causes the ending of other chromosomes to form a ring. This chromosomal abnormality causes the formation during the fetal stage to change, and causes development to be different than usual. This could affect all cells, however it usually only affects a small handful of them.
== History ==
This conditionsyndrome was first reported in 1964.<ref>https://en.wikipedia.org/wiki/Ring_chromosome_18</ref>
== FlagReferences ==
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The flag was designed by FANDOM user Poggingcameron on April 30th of 2021. The blue signifies the lack of a missing or undescended testicle, the ring represents the chromosomes ending in a ring, and the minus signifies the lack of estimated people with the condition
Chromosome 18 Ring is a syndrome that - in some cases - may be considered an intersex variation, although many would say it causes intersex traits rather than being one in of itself. This syndrome is seemingly rare, with no known estimates.
This syndrome can cause a missing or undescended testicle, a micropenis, and/or hypospadias in CTM/AMAB individuals. CTF/AFAB individuals with this syndrome tend to have labial hypoplasia (one or both labia missing.)
This syndrome often comes with low muscle tone, strabismus, hearing loss, undersized kidneys, foot abnormalities, scoliosis, rib-cage abnormalities, umbilical and inguinal hernias, and brain defects that often lead one to fall on the autism spectrum. Some of these symptoms may classify one with this syndrome as physically disabled.[1]
Causes
This syndrome is caused when there is a defect, loss, or deletion in the 18th chromosome, which causes the ending of other chromosomes to form a ring. This chromosomal abnormality causes the formation during the fetal stage to change, and causes development to be different than usual. This could affect all cells, however it usually only affects a small handful of them.