H Syndrome, Histiocytosis-Lymphadenopathy Plus Syndrome, or PHID, is a syndrome that may or may not be considered an intersex variation, or it may be considered a syndrome that comes with intersex traits, depending on who you ask.[1]
Those with this syndrome tend to have hypogonadism, darker skin than usual for their race (hyperpigmentation), more hair growth than usual (hypertrichosis), hearing loss, heart anomalies, low height, hyperglycemia, hallux valgus, and hepatosplenomegaly (enlarged spleen and liver).
It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this syndrome, as someone may only experience one or several of these symptoms, yet still hold the syndrome.
Causes
This syndrome is caused by a mutation within the SLC29A3 gene, which is a gene that helps encode important proteins within the biological human body.
History
This syndrome was first described in 1998.[2]
Flag
The H Syndrome flag was coined by Reign of the breadsticcs on May 7th of 2021. It has no confirmed meaning.[3]
Etymology
This syndrome was named "H Syndrome" due to most of the symptoms starting with the letter H.