Familial Male-Limited Precocious Puberty (FMPP), Familial Sexual Precocity, or Gonadotropin-Independent Testotoxicosis is an intersex variation that effects AMAB and/or CTM individuals. It is unknown how common it is, however it is rare.[1]
Those with this variation hit an early puberty, beginning sexual development at the ages of 2-5. This may cause a lot of confusion within the child, as their mind is not yet developed to understand these changes within their body.
The changes include body hair, acne, a deepening voice, spontaneous erections, penile growth, sexual desire/interest at an early age (unless they are ace-spec and/or not sex-favorable,) and increased height. Those with this variation tend to stop growing at a very early age, due to their early puberty, and tend to be shorter than the rest of their family. Those with this variation also have CTM hyperandrogenism, which is one of the reasons for their early puberty.[2]
Causes
This variation is caused by mutations in the LHCGR gene. The LHCGR gene provides instructions for proteins that luteinize the hormone/chorionic gonadotropin receptor, which is what causes a stable development in androgens and other hormones.[3]
Because of this gene mutation, hormonal activity tends to begin early and at an increased rate, causing the individual to grow masculine traits at an early age.
Flag
The FMPP flag was coined by Reign of the breadsticcs on May 7th of 2021. It has no confirmed meaning.
References
- ↑ https://archive.today/https://medlineplus.gov/genetics/condition/familial-male-limited-precocious-puberty/#frequency
- ↑ https://archive.today/https://medlineplus.gov/genetics/condition/familial-male-limited-precocious-puberty/
- ↑ https://archive.today/https://medlineplus.gov/genetics/condition/familial-male-limited-precocious-puberty/#causes