Chromosome 18 Ring

Chromosome 18 Ring is a syndrom that - in some cases - may be considered an intersex variation, although many would say it causes intersex traits rather than being one in of itself. This syndrome is seemingly rare, with no known estimates. This syndrome can cause a missing or undescended testicle, a micropenis, and/or hypospadias in CTM/AMAB individuals. Amongst CTF/AFAB individuals with this syndrome tend to have labial hypoplasia (one or both labias missing.)

This syndrome often comes with low muscle tone, strabismus, hearing loss, undersized kidneys, foot abnormalties, scoliosis, rib-cage abnormalities, umbilical and inguinal hernias, and brain defects that often lead one to fall on the autism spectrum.

It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this syndrome, as someone may only experience one or several of these symptoms, yet still hold the syndrome.

Causes
This syndrome is caused when there is a defect, loss, or deletion in the 18th chromosome, which causes the ending of other chromosomes to form a ring. This chromosomal abnormality causes the formation during the fetal stage to change, and causes development to be different than usual. This could affect all cells, however it usually only affects a small handful of them.

History
This syndrome was first reported in 1964.

Flag
The flag was designed by FANDOM user Poggingcameron on April 30th of 2021. The blue signifies the missing or undescended testicle, the ring represents the chromosomes ending in a ring, and the minus signifies the lack of estimated people with the syndrome.

Resources

 * https://rarediseases.org/rare-diseases/chromosome-18-ring/
 * https://en.wikipedia.org/wiki/Ring_chromosome_18